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Ibrutinib Cost in India
Ibrutinib is used to treat certain cancers (such as mantle cell lymphoma, chronic lymphocytic leukemia, Waldenstrom macroglobulinemia). Imbruvica (Ibrutinib Cost) belongs to a class of kinase inhibitors, which work by slowing or stopping the growth of cancer cells.
Imbruvica (Ibrutinib) is also used to treat a certain problem that may occur after a stem cell transplant (chronic graft versus host disease). Ibrutinib works by weakening your body’s immune system.
Some other side effects of a drug that are not listed on the approved drug label, but your doctor may direct you to take. You should only use this medicine to treat certain other medical conditions when prescribed by your doctor.
The information provided is not a substitute for medical professional advice. Always consult your doctor or pharmacist before deciding to take a medication.
What is the adult dose of ibrutinib?
Usual Adult Dose for Lymphoma
- Mantle cell lymphoma (MCL) or marginal zone lymphoma (MZL): you take 560mg, once a day.
- Duration of treatment until disease progression or unacceptable drug toxicity.
- Usual Adult Dose with Chronic Lymphocytic Leukemia
- Chronic Lymphocytic Leukemia (CLL) / Small Cell Lymphocytic Leukemia (SLL):
- Therapeutic dose: you take 420mg once a day.
- Combined with bendamustine and rituximab : you take 420mg, taken once a day, every 28 days to 6 cycles.
- Duration of treatment until disease progression or unacceptable drug toxicity.
Usual Adult Dose for Non-Hodgkin’s Lymphoma
Waldrostrom’s disease (WM) or transfusion-associated graft-versus-host disease (cGVHD): you take 420mg, once a day.
- Waldrostrom’s disease: until disease progression or unacceptable drug toxicity.
- Transfusion-induced graft-versus-host disease: until disease progression, recurrence of an underlying malignancy or unacceptable drug toxicity.
What is the dose of ibrutinib for children?
Consult your doctor before using ibrutinib in children.
How should I take ibrutinib?
Swallow the tablet whole with a full glass of water (240ml) as directed by your doctor, usually once daily.
If you take too much, your condition will not improve any faster and your risk of serious side effects will increase.
Because this medicine can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or may become pregnant should not take this medicine or breathe dust from the capsules.
If you have any questions about taking your medicine, ask your doctor or pharmacist.
What should you do in case of an overdose?
In the event of an emergency or overdose, immediately call 911 or go to the nearest local health station.
Also, keep a record and bring a list of all the medications you take, including prescription and over-the-counter drugs.
What should you do if you miss a dose?
If you forget to take a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Do not take double the prescribed dose.
What side effects will you experience while taking ibrutinib?
- Abdominal pain, diarrhea, nausea, vomiting, loss of appetite, headache, joint/muscle pain, swelling ankles/legs, numbness/tingling of arms/legs, anxiety, constipation, dizziness or fatigue. If any of these effects persist or worsen, tell your doctor right away.
- Remember that your doctor prescribes this medicine because they judge that the benefit to you outweighs the risk of side effects. Many people who use this drug have no serious side effects.
- This medicine may increase your blood pressure. Check your blood pressure regularly and let your doctor know if the results are high. Your doctor can control your blood pressure with medication.
- Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, black/red/bloody stools, fast/irregular heartbeat, signs of a low red blood cell count (such as rapid breathing, pale skin, difficulty breathing).
- Imbruvica Cost sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To reduce your risk, your doctor may add medication and ask you to drink plenty of fluids. Tell your doctor right away if you have symptoms such as: back/side pain, signs of kidney problems (such as painful urination, pink/bloody urine, change in the amount of urine), muscle spasms corny/weak.
- This medicine may decrease the body’s ability to fight infections. This can make you more susceptible to serious (rarely fatal) infections. Tell your doctor right away if you have any signs of an infection (such as fever, chills, persistent sore throat, cough).
- Very rarely, people taking this medicine get other types of cancer (including skin cancer ). Consult your doctor for more details.
- Get emergency medical help right away if you have any serious side effects, including: chest pain, signs of bleeding in the brain (such as fainting, sudden vision changes, severe nausea, convulsions, confusion).
- Very serious allergic reactions to this medicine are rare. However, get emergency medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness , shortness of breath.
This is not a complete list of side effects and others may occur. If you have any questions about side effects, consult your doctor or pharmacist.
What should you pay attention to before taking ibrutinib?
Before taking this medicine, you should tell your doctor or pharmacist if:
- You are allergic to any of the ingredients in the medicine.
- You have or have ever had: blood/bleeding problems, heart problems (such as fast/irregular heartbeat, previous heart attack), high blood pressure, kidney problems, problems liver problems, high levels of uric acid in the blood.
- Do not get vaccinated without your doctor’s consent. Avoid contact with people who have recently received a live vaccine.
- To reduce your risk of being cut, bruised, or injured, use caution with sharp objects such as razors and nail clippers, and avoid activities such as contact sports.
- Before surgery, tell your doctor or dentist about all the products you use (including prescription drugs, over-the-counter medicines, and herbal products). Your doctor may ask you to stop treatment with this medicine before having certain medical, surgical, or dental procedures.
- Because this medicine can be absorbed through the skin and lungs, which could harm an unborn baby, women who are pregnant or may become pregnant should not take this medicine or breathe dust from the capsule.
- Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while taking ibrutinib cost. may harm an unborn baby. Men and women should ask about reliable forms of birth control while taking this medicine and for 1 month after stopping treatment. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
- It is not known whether this medicine passes into breast milk. Because of the possible risk to the infant, women who are breastfeeding are not recommended to take this medicine. Consult your doctor before breast-feeding.
What drugs can interact with ibrutinib?
ibrutinib may change how other medicines you are taking work or increase the effects of side effects. To avoid drug interactions, it’s best to write down a list of all the medications you’re taking (including prescription, over-the-counter, herbal and dietary supplements) and show them to your doctor or pharmacist. To ensure safety when taking the drug, do not arbitrarily take the drug, stop or change the dose of the drug without the permission of the doctor.
Drugs that may interact with ibrutinib include: other drugs that can cause bleeding/bruising (eg, antiplatelet drugs – clopidogrel, nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen /naproxen), thinners blood, such as warfarin /dabigatran).
Aspirin may increase the risk of bleeding when taken with this medicine. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at doses of 81-325 milligrams per day), you should continue to take it unless your doctor directs you otherwise. Ask your doctor or pharmacist for more details.
Other drugs may affect the removal of ibrutinib price from your body, which may affect how ibrutinib works. These include azole antifungals (such as itraconazole, ketoconazole), boceprevir, nefazodone , St. John’s wort, telaprevir, HIV protease inhibitors (such as ritonavir, saquinavir), macrolide antibiotics (such as erythromycin, clarithromycin), rifamycins (such as rifampin, rifabutin), certain drugs used to treat seizures (such as carbamazepine) , phenytoin) and some other drugs.
Can ibrutinib interact with any food or drink?
Food, alcohol, and tobacco can interact with certain medications. Consult your doctor about taking your medicine with food, alcohol and tobacco.
Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you can do so.
This medicine may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machines, or do anything that requires alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana.
What health conditions affect ibrutinib?
Your medical condition may affect the use of this medicine. Tell your doctor if you have any health problems.
Ibrutinib may make you more susceptible to infections or may worsen any existing infections. Therefore, you should wash your hands thoroughly to prevent the spread of infection. Avoid contact with people who have infections that can be spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been in contact with an infected person or for more details.
How should ibrutinib be stored?
You should store at room temperature, away from moisture and light. Do not store in the bathroom or in the freezer. You should keep in mind that each medicine may have different storage methods. Therefore, you should carefully read the storage instructions on the packaging or ask the pharmacist. Keep medicine out of reach of children and pets.
You should not throw medicine down the toilet or plumbing unless told to do so. Instead, dispose of medication properly when it is past its expiration date or cannot be used. You can consult your pharmacist or local waste disposal company about how to safely dispose of your medication.
- Ibrutinib cost is available in tablet and capsule form.
- Hello Health Group does not provide medical advice, diagnoses or treatments.
Hello Basic’s articles are for reference only and are not a substitute for medical diagnosis or treatment.